2024

Zarp, J. Bruun, C. F. Christiansen, S. T. Krogh, H. B. Kuchinke, O. V. Bernsen, C. L. Jespersen, A. E. Bardram, J. E. Kessing, L. V. Miskowiak, K. W. Web-based cognitive screening in bipolar disorder: Validation of the Internet-based Cognitive Assessment Tool in remote administration settings Nordic Journal of Psychiatry. 2024 (in press).

Macoveanu J, Zarp J, Vinberg M, Brendstrup-Brix K, Kessing LV, Jørgensen MB, Miskowiak K. Exploring the effects of erythropoietin treatment on cortical thickness and hippocampal volume in patients with mood disorders undergoing electroconvulsive therapy: a randomized, placebo-controlled trial Journal of Psychopharmacology. 2024 (in press).

Kjaerstad HL, Jespersen AE, Bech JL, Weidemann S, Bjertrup AJ, Jacobsen EH, Simonsen S, Glenthøj LB, Nordentoft M, Reveles K, Wøbbe T, Lopes M, Lyngholm D, Miskowiak K. Optimizing differential diagnostics and identifying transdiagnostic treatment targets using virtual reality European Neuropsychopharmacology. 2024 (in press).

Jespersen AE, Lumbye A, Mariegaard J, Damgaard V, Glenthoj LB, Nordentoft M, Mikkelsen C, Didriksen M, Ostrowski SR, Vinberg M, Waehrens EE, Miskowiak KW. Cognition Assessment in Virtual Reality (CAVIR): Associations with neuropsychological performance and activities of daily living in patients with mood or psychosis spectrum disorders J Affect Disord. 2024.

Thommesen KK, Damgaard V, Mariegaard J, Jespersen AE, Ysbæk-Nielsen AT, Mikkelsen C, Didriksen M, Ostrowski SR, Jørgensen MB, Macoveanu J, Miskowiak K. Neural underpinnings of memory encoding and retrieval: Validation of a novel ecologically valid fMRI paradigm Neuroscience Applied. 2024 (in press).

Petersen JZ, Macoveanu J, Ysbaek-Nielsen AT, Kessing LV, Jorgensen MB, Miskowiak KW Neural correlates of episodic memory decline following electroconvulsive therapy: An exploratory functional magnetic resonance imaging study J Psychopharmacol. 2024;38(2):168-77.

Miskowiak KW, Roikjer TK, Mariegaard J, Bech JL, Obel ZK, Vejstrup B, Hansen L, Kessing LV Implementing cognitive screenings for outpatients with bipolar disorder following optimised treatment in a specialised mood disorder clinic Eur Neuropsychopharmacol. 2024;84:27-34.

Miskowiak KW, Petersen JZ, Macoveanu J, Ysbaek-Nielsen AT, Lindegaard IA, Cramer K, Mogensen MB, Hammershoj LG, Stougaard ME, Jorgensen JL, Schmidt LS, Vinberg M, Ehrenreich H, Hageman I, Videbech P, Gbyl K, Kellner CH, Kessing LV, Jorgensen MB Effect of erythropoietin on cognitive side-effects of electroconvulsive therapy in depression: A randomized, double-blind, placebo-controlled trial Eur Neuropsychopharmacol. 2024;79:38-48.

Miskowiak KW, Obel ZK, Guglielmo R, Bonnin CDM, Bowie CR, Balanza-Martinez V, Burdick KE, Carvalho AF, Dols A, Douglas K, Gallagher P, Kessing LV, Lafer B, Lewandowski KE, Lopez-Jaramillo C, Martinez-Aran A, McIntyre RS, Porter RJ, Purdon SE, Schaffer A, Stokes PRA, Sumiyoshi T, Torres IJ, Van Rheenen TE, Yatham LN, Young AH, Vieta E, Hasler G Efficacy and safety of established and off-label ADHD drug therapies for cognitive impairment or attention-deficit hyperactivity disorder symptoms in bipolar disorder: A systematic review by the ISBD Targeting Cognition Task Force Bipolar Disord. 2024;26(3):216-39.

Miskowiak KW, Kjaerstad HL Can cognition screening in the clinic aid personalised treatment in bipolar disorder? Eur Neuropsychopharmacol. 2024;81:10-1.

Miskowiak KW, Damgaard V, Schandorff JM, Macoveanu J, Knudsen GM, Johansen A, Plaven-Sigray P, Svarer C, Fussing CB, Cramer K, Jørgensen MB, Kessing LV, Ehrenreich H Effects of cognitive training under hypoxia on cognitive proficiency and neuroplasticity in remitted patients with mood disorders and healthy individuals: ALTIBRAIN study protocol for a randomized controlled trial Trials. 2024;25(1):648.

Macoveanu J, Zarp Petersen J, Mariegaard J, Elleby Jespersen A, Cramer K, Fussing Bruun C, Østergaard Madsen H, Balslev Jørgensen Dmsc M, Vinberg Dmsc M, Fisher PM, Moos Knudsen G, Hageman I, Ehrenreich Dmsc H, Vedel Kessing Dmsc L, Woznica Miskowiak Dmsc K Effects of erythropoietin on cognitive impairment and prefrontal cortex activity across affective disorders: A randomized, double-blinded, placebo-controlled trial Running title: Treatment of cognitive impairment 2024.

Macoveanu J, Kjaerstad HL, Halvorsen KS, Fisher PM, Vinberg M, Kessing LV, Miskowiak KW Trajectory of reward-related abnormalities in unaffected relatives of patients with bipolar disorder – A longitudinal fMRI study J Psychiatr Res. 2024;170:217-24.

Macoveanu J, Fortea L, Kjaerstad HL, Coello K, Faurholt-Jepsen M, Fisher PM, Knudsen GM, Radua J, Vieta E, Frangou S, Vinberg M, Kessing LV, Miskowiak KW Longitudinal changes in resting-state functional connectivity as markers of vulnerability or resilience in first-degree relatives of patients with bipolar disorder Psychol Med. 2024:1-9.

Kjaerstad HL, de Siqueira Rotenberg L, Macoveanu J, Coello K, Faurholt-Jepsen M, Bjertrup AJ, Knudsen GM, Fisher PM, Vinberg M, Kessing LV, Lafer B, Miskowiak KW Stable neural underpinnings of emotional cognition subgroups in patients newly diagnosed with bipolar disorder: A prospective fMRI study Bipolar Disord. 2024.

Jespersen AE, Obel Z, Lumbye A, Kessing LV, Miskowiak KW Bipolar-ADHD comorbidity: screening for differences in neurocognition and virtual reality-based cognitive performance Nord J Psychiatry. 2024;78(3):238-46.

Jespersen AE, Lumbye A, Vinberg M, Glenthoj L, Nordentoft M, Waehrens EE, Knudsen GM, Makransky G, Miskowiak KW Effect of immersive virtual reality-based cognitive remediation in patients with mood or psychosis spectrum disorders: study protocol for a randomized, controlled, double-blinded trial Trials. 2024;25(1):82.

Bjertrup AJ, Kofoed J, Egmose I, Wendelboe K, Southgate V, Vaever MS, Miskowiak KW Prenatal affective cognitive training to reduce the risk of postpartum depression (PACT): study protocol for a randomized controlled trial Trials. 2024;25(1):478.

Bjertrup AJ, Jahn FS, Schutt Hansen L, Miskowiak KW Affective cognition in response to infant stimuli in pregnant compared with non-pregnant women Women Health. 2024;64(5):427-39.

2023

Miskowiak, KW; Simonsen, AH; Meyer, M; Poulsen, HE; Wilkan, M; Forman, J; Hasselbalch, SG; Kessing, LV; Knorr, U Cerebrospinal fluid erythropoietin, oxidative stress, and cognitive functions in patients with bipolar disorder and healthy control participants: A longitudinal case-control study J Psychiatr Res, 2023 vol. 163 pp. 240-246​

Jørgensen, JL; Macoveanu, J; Petersen, JZ; Knudsen, GM; Kessing, LV; Jørgensen, MB; Miskowiak, KW Association of childhood trauma with cognitive impairment and structural brain alterations in remitted patients with bipolar disorder J Affect Disord, 2023 S0165-0327(23)00719-X  ​​     ​

Miskowiak, KW;​​ Kjærstad, HL; Lemvigh, CK; Ambrosen, KS; Thorvald, MS; Kessing, LV; Glenthoj, BY; Ebdrup, BH; Fagerlund, B Neurocognitive subgroups among newly diagnosed patients with schizophrenia spectrum or bipolar disorders: A hierarchical cluster analysis J Psychiatr Res, 2023 vol. 163 pp. 278-287

Sankar A, Ozenne B, Dam VH, Svarer C, Jørgensen MB, Miskowiak KW, Frokjaer VG, Knudsen GM, Fisher PM. Association between brain serotonin 4 receptor binding and reactivity to emotional faces in depressed and healthy individuals. Transl Psychiatry. 2023 May 11;13(1):165. doi: 10.1038/s41398-023-02440-3.PMID: 37169780 Free PMC article.

Bjertrup AJ, Væver MS, Miskowiak KW. Prediction of postpartum depression with an online neurocognitive risk screening tool for pregnant women. Eur Neuropsychopharmacol. 2023 Apr 27;73:36-47. doi: 10.1016/j.euroneuro.2023.04.014. Online ahead of print.PMID: 37119561 Free article.

Macoveanu J, Mariegaard J, Petersen JZ, Fisher PM, Vinberg M, Jørgensen MB, Knudsen GM, Kessing LV, Miskowiak KW. Neural basis of memory impairments and relation to functional disability in fully or partially remitted patients with affective disorders. Prog Neuropsychopharmacol Biol Psychiatry. 2023 Jul 13;125:110767. doi: 10.1016/j.pnpbp.2023.110767. Epub 2023 Apr 15.PMID: 37068543 Free article.

Macoveanu J, Petersen JZ, Fisher PM, Kessing LV, Knudsen GM, Miskowiak KW. Associations between aberrant working memory-related neural activity and cognitive impairments in somatically healthy, remitted patients with mood disorders. Psychol Med. 2023 Apr 13:1-11. doi: 10.1017/S0033291723000715. Online ahead of print.PMID: 37051904

Kjærstad HL, Macoveanu J, Knudsen GM, Frangou S, Phan KL, Vinberg M, Kessing LV, Miskowiak KW. Neural responses during down-regulation of negative emotion in patients with recently diagnosed bipolar disorder and their unaffected relatives. Psychol Med. 2023 Mar;53(4):1254-1265. doi: 10.1017/S0033291721002737. Epub 2021 Aug 31.PMID: 37010225

Sankar A, Ziersen SC, Ozenne B, Beaman EE, Dam VH, Fisher PM, Knudsen GM, Kessing LV, Frokjaer V, Miskowiak KW. Association of neurocognitive function with psychiatric hospitalization and socio-demographic conditions in individuals with bipolar and major depressive disorders. EClinicalMedicine. 2023 Mar 24;58:101927. doi: 10.1016/j.eclinm.2023.101927. eCollection 2023 Apr.PMID: 37007740 Free PMC article.

de Siqueira Rotenberg L, Kjærstad HL, Varo C, Vinberg M, Kessing LV, Lafer B, Miskowiak KW. The longitudinal trajectory of emotional cognition in subgroups of recently diagnosed patients with bipolar disorder. Eur Neuropsychopharmacol. 2023 Mar 23;71:9-24. doi: 10.1016/j.euroneuro.2023.03.005. Online ahead of print.PMID: 36965236 Free article.

Agger MP, Danielsen ER, Carstensen MS, Nguyen NM, Horning M, Henney MA, Jensen CBR, Baandrup AO, Kjær TW, Madsen KH, Miskowiak K, Petersen PM, Høgh P.J Safety, Feasibility, and Potential Clinical Efficacy of 40 Hz Invisible Spectral Flicker versus Placebo in Patients with Mild-to-Moderate Alzheimer’s Disease: A Randomized, Placebo-Controlled, Double-Blinded, Pilot Study. Alzheimers Dis. 2023;92(2):653-665. doi: 10.3233/JAD-221238.PMID: 36776073 Clinical Trial.

Kjærstad, HL; Varo, C; Meluken, I; Vieta, E; Vinberg, M; Kessing, LV; Miskowiak, KW Emotional cognition subgroups in unaffected first-degree relatives of patients with mood disorders Psychol Med, 2023 vol. 53(6) pp. 2328-2338

Miskowiak, KW; Kjærstad, HL; Lemvigh, CK; Ambrosen, KS; Thorvald, MS; Kessing, LV; Glenthoj, BY; Ebdrup, BH; Fagerlund, B Neurocognitive subgroups among newly diagnosed patients with schizophrenia spectrum or bipolar disorders: A hierarchical cluster analysis​ J Psychiatr Res, 2023 vol. 163 pp. 278-287​

​Miskowiak, KW; Simonsen, AH; Meyer, M; Poulsen, HE; Wilkan, M; Forman, J; Hasselbalch, SG; Kessing, LV; Knorr, U Cerebrospinal fluid erythropoietin, oxidative stress, and cognitive functions in patients with bipolar disorder and healthy control participants: A longitudinal case-control study  J Psychiatr Res, 2023 vol. 163 pp. 240-246​

Miskowiak KW, Bech JL, Henriksen AC, Johnsen S, Podlekareva D, Marner L Cerebral Metabolic Rate of Glucose and Cognitive Tests in Long COVID Patients ​ Brain Sci. 2022, 13(1):23​

Macoveau J, Damgaard V, Ysbæk-Nielsen AT, Frangou S, Yatham LN, Chakrabarty T, Stougaard ME, Knudsen GM, Vinberg M, Kessing LV, Kjaerstad HL, Miskowiak KW Early longitudinal changes in brain structure and cognitive functioning in remitted patients with recently diagnosed bipolar disorder​ J Affect Disord. 2023, 339:153-161

Bjertrup, AJ; Petersen, TH; Beier, N; Kofoed, J; Horgen, IÅ; Tjærbye-Thygesen, A; Kirkegaard, T, Miskowiak, KW Prenatal affective cognitive training: A proof-of-concept study​ J.nsa.2023.101135

Miskowiak KW, Hansen KB, Mariegaard J, Kessing LV Association between childhood trauma, cognition, and psychosocial function in a large sample of partially or fully remitted patients with bipolar disorder and healthy participants  Int J of Bipolar Disorder 11(​​1):31    

Fortea L, Ysbæk-Nielsen AT, Macoveanu J, Petersen JZ, Fisher PM, Kessing LV, Knudsen GM, Radua J, Vieta E, Miskowiak KW​  Aberrant resting-state functional connectivity underlies cognitive and functional impairments in remitted patients with bipolar disorder   Acta Psychiatr Scand 1-13​​

Sankar A, Ziersen SC, Ozenne B, Beaman EE, Dam VH, Fisher PM, Knudsen GM, Kessing LV, Frokjaer V, Miskowiak KW Association of neurocognitive function with psychiatric hospitalization and socio-demographic conditions in individuals with bipolar and major depressive disorders​ Lancet J:eClinicalMed 58:101927

Damgaard V, Mariegaard J, Lindhardsen JM, Ehrenreich H, Miskowiak KW Neuroprotective Effects of Moderate Hypoxia: A Systematic Review​ Brain Sci. 13(12):1648

Petersen JZ, Macoveanu J, Ysbæk-Nielsen AT, Kessing LV, Jørgensen MB, Miskowiak KW Neural correlates of episodic memory decline following electroconvulsive therapy: An exploratory functional magnetic resonance imaging study J Psychopharmacol. 2023 Dec 30:2698811231221153. doi: 10.1177/02698811231221153. Online ahead of print

Macoveanu J, Kjærstad HL, Halvorsen KS, Fisher PM, Vinberg M, Kessing LV, Miskowiak KW Trajectory of reward-related abnormalities in unaffected relatives of patients with bipolar disorder – A longitudinal fMRI study J Psychiatr Res. 2023 Dec 25;170:217-224. doi: 10.1016/j.jpsychires.2023.12.035. Online ahead of print.

Damgaard V, Mariegaard J, Lindhardsen JM, Ehrenreich H, Miskowiak KW Neuroprotective Effects of Moderate Hypoxia: A Systematic Review Brain Sci. 2023 Nov 27;13(12):1648. doi: 10.3390/brainsci13121648.

Miskowiak KW, Petersen JZ, Macoveanu J, Ysbæk-Nielsen AT, Lindegaard IA, Cramer K, Mogensen MB, Hammershøj LG, Stougaard ME, Jørgensen JL, Schmidt LS, Vinberg M, Ehrenreich H, Hageman I, Videbech P, Gbyl K, Kellner CH, Kessing LV, Jørgensen MB Effect of erythropoietin on cognitive side-effects of electroconvulsive therapy in depression: A randomized, double-blind, placebo-controlled trial Eur Neuropsychopharmacol. 2023 Dec 20;79:38-48. doi: 10.1016/j.euroneuro.2023.12.004. Online ahead of print.

2022

Miskowiak KW, Pedersen JK, Gunnarsson DV, Roikjer TK, Podlekareva D, Hansen H, Dall CH, Johnsen S Cognitive impairments among patients in a long-COVID clinic: Prevalence, pattern and relation to illness severity, work function and quality of life J Affect Disord. 2022 Dec 28;324:162-169. doi: 10.1016/j.jad.2022.12.122. Online ahead of print

Kjærstad HL, Søhol K, Vinberg M, Kessing LV, Miskowiak KW The trajectory of emotional and non-emotional cognitive function in newly diagnosed patients with bipolar disorder and their unaffected relatives: A 16-month follow-up study  Eur Neurop. 2022 Nov 30;67:4-21. doi: 10.1016/j.euroneuro.2022.11.004. Online ahead of print

Macoveanu J, Stougaard ME, Kjærstad HL, Knudsen GM, Vinberg M, Kessing LV, Miskowiak KW Trajectory of aberrant reward processing in patients with bipolar disorder – A longitudinal fMRI study  J Affect Disord. 2022 Sep 1;312:235-244. doi:
10.1016/j.jad.2022.06.053. Epub 2022 Jun 26

Kjærstad HL, Hellum KS, Haslum NH, Lopes MN, Noer TZ, Kessing LV, Miskowiak KW Assessment of the validity and feasibility of a novel virtual reality test of emotion regulation in patients with bipolar disorder and their unaffected relatives​  J Affect Disord. 2022 Sep 8;S0165-0327(22)00999-5. doi: 10.1016/j.jad.2022.09.004. Online ahead of print

Kjærstad HL, Haldorsen T, Vinberg M, Kessing LV, Miskowiak KW ​Associations between emotional and non-emotional cognition and subsequent mood episodes in recently diagnosed patients with bipolar disorder  J Affect Disorders 2022, 324: 16-23

​​Miskowiak KW, Seeberg I, Jensen MB, Balanza-Martinez V, Bonnin  CDM, Bowie CR, Carvalho AF, Dols A, Douglas K, Gallagher P, Hasler G, Lafer B, Lewandowski KE, Lopez-Jaramillo C, Martinez-Aran A, McIntyre RS, Porter RJ, Purdon SE, Schaffer A, Stokes P, Sumiyoshi T, Torres IJ, Rheenen TEV, Yatham LN, Young AH, Kessing LV, Burdick KE, Vieta E Randomised controlled cognition trials in remitted patients with mood disorders published between 2015 and 2021: A systematic review by the International Society for Bipolar Disorders Targeting Cognition Task Force Bipolar Disord. 2022 Jun;24(4):354-374. doi.10.1111/bdi.13193. Epub 2022 Feb 24

M​iskowiak KW, Yalin N, Seeberg I, Burdick KE, Balanzá-Martínez V, Bonnin CDM, Bowie CR, Carvalho AF, Dols A, Douglas K, Gallagher P, Hasler G, Kessing LV, Lafer B, Lewandowski KE, López-Jaramillo C, Martines-Aran A, McIntyre RS, Porter RJ, Purdon SE, Schaffer A, Sumiyoshi T, Torres IJ, Rheenen TEV, Yatham LN, Young AH, Vieta E, Stokes PRA Can magnetic resonance imaging enhance the assessment of potential new treatments for cognitive impairment in mood disorders? A systematic review and position paper by the International Society for Bipolar Disorders Targeting Cognition Task Force​ Bipolar disord. 2022 Aug 11., 24(6): 615-636. doi: 10.1111/bdi.13247.

​Kjærstad HL, Rotenberg LdS, Knudsen GM, Vinberg M, Kessing LV, Macoveanu J, Lafer B, Miskowiak KW  The longitudinal trajectory of emotion regulation and associated neural activity in patients with bipolar disorder: A prospective fMRI study​ Acta Pschiatr Scand. 2022 Aug 14, 146(6): 568-582. doi: 10.1111/acps.13488.

Kjærstad HL, Poulsen E, Vinberg M, Kessing LV, Miskowiak KW Differential trajectory of cognitive functions in neurocognitive subgroups of newly diagnosed patients with bipolar disorder and their unaffected first-degree relatives – A longitudinal study J Affect Disord. 2022 Aug 15;311:115-125. doi: 10.1016/j.jad.2022.05.045. Epub 2022 May 14

Kjærstad HL, Damgaard V, Knudsen GM, Vinberg M, Kessing LV, Macoveanu J, Miskowiak KW Neural underpinnings of emotion regulation subgroups in remitted patients with recently diagnosed bipolar disorder Eur Neuroph. 2022 May 9;60:7-18. doi 10.1016/j.euroneuro.2022.04.010​​​​​

Miskowiak KW, Fugledalen L, Jespersen AE, Sattler SM, Podlekareva D, Rungby J, Porsberg CM, Johnsen S Trajectory of cognitive impairments over 1 year after COVID-19 hospitalisation: Pattern, severity, and functional implications  Eur Neuroph. 2022 Apr 14;59:82-92. doi: 0.1016/j.euroneuro.2022.04.004

Nielsen SL, Ludwigsen T, Johnsen S, Miskowiak KW [Cognitive late sequelae of COVID-19]​Ugeskr Laeger. 2022 Apr 11: 184(15):V09210730. Article in Danish

Hørlyck LD, Jespersen AE, King JA, Ullum H, Miskowiak KW, Impaired allocentric spatial memory in patients with affective disorders J Psychiartr Res, 2022 vol. 150 pp. 153-159​

Mogensen MB, Macoveanu J, Knudsen GM, Ott CV, Miskowiak KW Influence of pre-treatment structural brain measures on effects of action-based cognitive remediation on executive function in partially or fully remitted patients with bipolar disorder Eur Neuropsychopharmacol. 2022 Mar;56: 50-59. doi: 10.1016/ j.euroneuro.2021.11.010. Epub 2021 Dec 20

Hammershøj LG, Petersen JZ, Jensen HM, Jørgensen MB, Miskowiak KW Cognitive Adverse Effects of Electroconvulsive Therapy: A Discrepancy Between Subjective and Objective Measures? ​ J ECT. 2022 Mar 1; 38(1): 30-38. doi: 10.1097

Miskowiak, KW; Seeberg, I; Jensen, MB; Balanzá-Martínez, V; Del Mar Bonnin, C; Bowie, CR; Carvalho, AF; Dols, A; Douglas, K; Gallagher, P; Hasler, G; Lafer, B; Lewandowski, KE; López-Jaramillo, C; Martinez-Aran, A; McIntyre, RS; Porter, RJ; Purdon, SE; Schaffer, A; Stokes, P; Sumiyoshi, T; Torres, IJ; Van Rheenen, TE; Yatham, LN; Young, AH; Kessing, LV; Burdick, KE; Vieta, E​​​​ Randomised controlled cognition trials in remitted patients with mood disorders published between 2015 and 2021: A systematic review by the International Society for Bipolar Disorders Targeting Cognition Task Force ​Bipolar Disord.  24(4): 354-374. 2022 Feb 16. doi: 10.1111/bdi.13193.

​​Petersen JZ, Varo C, Skovsen CF, Ott CV, Kjaerstad HL, Vieta E, Harmer CJ, Knudsen GM, Kessing LV, Macoveanu J, Miskowiak K Neuronal underpinnings of cognitive impairment in bipolar disorder: A large data-driven functional magnetic resonance imaging study Bipolar disord. 2022 Feb. doi: 10.1111/bdi. 13100. Epub 2021 Jun 18​​

​Miskowiak KW, Mariegaard J, Jahn FS, Kjærstad HL Associations between cognition and subsequent mood episodes in patients with bipolar disorder and their unaffected relatives: A systematic review​ J Affect Disord. 2022 Jan 15;297:176-188.doi: 10.1016/j.jad.2021.10.044. Epub 2021 Oct 24.​

Macoveanu J, Damgaard V, Ott CV, Knudsen, Kessing LV, Miskowiak KW Action-based cognitive remediation in bipolar disorder improved verbal memory but had no effect on the neural response during episodic memory encoding​ Psychiatry Res Neuroimaging 2022 Jan;319:111418. doi: 10.1016/j.pscychresns. 2021.111418. Epub 2021 Nov 23.​​

Bjertrup A, Macoveanu J, Laurent H, Moszkowicz M, Finnegan MK, Egmose I, Fisher P MD, Nielsen RE, Pagsberg AK, Kessing LV, Væver M, Miskowiak K Reduced prefrontal cortex response to own vs. unknown emotional infant faces in mothers with bipolar disorder​ Eur Neuropsychopharmacol. 2022 Jan; 54:720.doi: 10.1016/j.euroneuro. 2021.09.011. Epub 2021 Oct 24.​​

2021

​​Miskowiak, KW; Jespersen, AE; Kessing, LV; Aggestrup, AS; Glenthøj, LB; Nordentoft, M; Ott, CV; Lumbye, A Cognition Assessment in Virtual Reality: Validity and feasibility of a novel virtual reality test for real-life cognitive functions in mood disorders and psychosis spectrum disorders  ​​J Psychiatr Res, 2021 vol. 145 pp.​​ 182-189​

Mogensen MB, J Macoveau, Knudsen GM, Ott CV, Miskowiak KW Influence of pre-treatment structural brain measures on effects of action-based cognitive remediation on executive function in partially or fully remitted patients with bipolar disorder​ j.euroneuro.2021.11.010​

Macoveau J, Damgaard V, Ott Caroline V, Knudsen Gitte M, Kessing Lars V, Miskowiak Kamilla W Action-based cognitive remediation in bipolar disorder improved verbal memory but had no effect on the neural response during episodic memory encoding ​​​ Neuroimaging, 2022-01-01, Volume 319, Article 111418​​​​​​​

Kjærstad HL, Hellum KS, Haslum NH, Lopes MN, Noer TZ, Kessing LV, Miskowiak KW Assessment of the validity and feasibility of a novel virtual reality test of emotion regulation in patients with bipolar disorder and their unaffected relatives​  J Affect Disord. 2022 Sep 8;S0165-0327(22)00999-5. doi: 10.1016/j.jad.2022.09.004. Online ahead of print

Macoveanu J, Freeman KO, Kjærstad HL, Knudsen GM, Kessing LV, Miskowiak KW Structural brain abnormalities associated with cognitive impairments in bipolar disorder Acta Psychiatr Scand. 2021;00:1–13

Varo C , Kjærstad HL, Poulsen E, Meluken I, Vieta E, Kessing LV, Maj Vinberg M , Miskowiak KW Emotional cognition subgroups in mood disorders: Associations with familial risk j.euroneuro.2021.05.003

Miskowiak, KW; Jespersen, AE; Obenhausen, K; Hafiz, P; Hestbæk, E; Gulyas, L; Kessing, LV; Bardram, JE, Internet-based cognitive assessment tool: Sensitivity and validity of a new online cognition screening tool for patients with bipolar disorder. J Affect Disord, 2021 vol. 289 pp. 125-134

Zarp Petersen, J; Varo, C; Skovsen, CF; Ott, CV; Kjaerstad, HL; Vieta, E; Harmer, CJ; Knudsen, GM; Kessing, LV; Macoveanu, J; Miskowiak, KW, Neuronal underpinnings of cognitive impairment in bipolar disorder: A large data-driven functional magnetic resonance imaging study. Bipolar Disord, 2021.

Petersen JZ, Macoveanu J, Kjærstad HI, Knudsen GM, Kessing LV, Miskowiak KW, Assessment of the neuronal underpinnings of cognitive impairment in bipolar disorder with a picture encoding paradigm and methodological lessons learnt J Psychopharmacol. 2021 Aug.

Bjertrup AJ, Moszkowicz M, Egmose I, Kjærbye-Thygesen A, René E Nielsen RE, Parsons CE, Kessing LV, Pagsberg AK, Væver MS, Miskowiak KW Processing of infant emotion in mothers with mood disorders and implications for infant development Psychol Med. 2021 Apr 19;1-11

Jahn F.S., Skovbye M, Obenhausen K, Jespersen A.E., Miskowiak K., Cognitive training with fully immersive virtual reality in patients with neurological and psychiatric disorders: A systematic review of randomized controlled trials Psychiatry Research 2021 Apr 6;300:113928

Ehrenreich H, Neubauer A-P, Miskowiak KW Effect of Early Recombinant Human Erythropoietin on Neurodevelopmental Outcomes at Age 5 Years JAMA. 2021;325(14):1470-1471

Miskowiak K., Johnsen S., Sattler S.M., Nielsen S., Kunalan K., Rungby J., Lapperre T., Porsberg C.M., Cognitive impairments four months after COVID-19 hospital discharge: Pattern, severity and association with illness variables European Neuropsychopharmacology 2021

Miskowiak K., Varo C., Social cognition in bipolar disorder: A proxy of psychosocial function and novel treatment target? European Neuropsychopharmacology 2021

Miskowiak KW, Møller AB, Caroline V Ott 3 Neuronal and cognitive predictors of improved executive function following action-based cognitive remediation in patients with bipolar disorder Eur Neuropsychopharmacol. 2021 Jun;47:1-10

Bjertrup A., Miskowiak K. Forstå dine hormoner under graviditet og efter fødsel engodstart.dk 2021

Bjertrup A., Miskowiak K. I risiko for fødselsdepression som mor? engodstart.dk 2021

Jensen M.B., Kjærstad H.L., Coello K., Stanislaus S., Melbye S., Sletved K. O., Vinberg M., Kessing L.V., Miskowiak K.W. Affective and non-affective cognition in patients with bipolar disorder type I and type II in full og partal remission: Associations with familial risk. J Affect Disord. 2021

Bjertrup A, Friis N, Væver M, Miskowiak K. Neurocognitive Processing of Infant Stimuli in Mothers and Non-Mothers: Psychophysiological, Cognitive and Neuroimaging Evidence. Soc Cogn Affect Neurosci. 2021 Jan 9:nsab002. doi: 10.1093/scan/nsab002. Epub ahead of print. PMID: 33420780.

Ott et al. Norms for the Screen for Cognitive Impairment inPsychiatry and cognitive trajectories in bipolar disorder. J Affect Disord. 2021 Feb 15;281:33-40.

2020

Hørlyck LD, Obenhausen K, Jansari A, Ullum H, Miskowiak KW. Virtual reality assessment of daily life executive functions in mood disorders: associations with neuropsychological and functional measures. J Affect Disord. 2020

Ott CV, Macoveanu J, Bowie CR, Fisher PM, Knudsen GM, Kessing LV, Miskowiak KW. Change in prefrontal activity and executive functions after action-based cognitive remediation in bipolar disorder: a randomized controlled trial. Neuropsychopharmacology. 2020

Bjertrup AJ, Jensen MB, Schjødt MS, Parsons CE, Kjærbye-Thygesen A, Mikkelsen RL, Moszkowicz M, Frøkjær VG, Vinberg M, Kessing LV, Væver MS, Miskowiak KW. Cognitive processing of infant stimuli in pregnant women with and without affective disorders and the association to postpartum depression. Eur Neuropsychopharmacol. 2020

Miskowiak KW. Erythropoietin as possible treatment of brain diseases. Ugeskr Laeger. 2020

Ott CV, Vinberg M, Kessing LV, Bowie CR, Forman JL, Miskowiak KW. Effect of Action-Based Cognitive Remediation on cognitive impairment in patients with remitted bipolar disorder: A randomized controlled trial. Bipolar Disord. 2020

Seeberg I, Nielsen IB, Jørgensen CK, Eskestad ND, Miskowiak KW. Effects of psychological and pharmacological interventions on anxiety symptoms in patients with bipolar disorder in full or partial remission: A systematic review. J Affect Disord. 2020

Macoveanu J, Meluken I, Kessing LV, Siebner HR, Vinberg M, Miskowiak KW. Hippocampal subfield morphology in monozygotic twins discordant for affective disorders. Neuropsychopharmacology. 2020

Ehrenreich H, Weissenborn K, Begemann M, Busch M, Vieta E, Miskowiak KW. Erythropoietin as candidate for supportive treatment of severe COVID-19. Mol Med. 2020

Ehrenreich H, Neubauer AP, Miskowiak K. Erythropoietin in Preterm Infants. N Engl J Med. 2020

Macoveanu J, Kjaerstad HL, Chase HW, Frangou S, Knudsen GM, Vinberg M, Kessing LV, Miskowiak KW. Abnormal prefrontal cortex processing of reward prediction errors in recently diagnosed patients with bipolar disorder and their unaffected relatives. Bipolar Disord. 2020

Petersen CS, Miskowiak KW. Toward a transdiagnostic neurocircuitry-based biomarker model for pro-cognitive effects: challenges, opportunities, and next steps. CNS Spectr. 2020

Macoveanu J, Meluken I, Chase HW, Phillips ML, Kessing LV, Siebner HR, Vinberg M, Miskowiak KW. Reduced frontostriatal response to expected value and reward prediction error in remitted monozygotic twins with mood disorders and their unaffected high-risk co-twins. Psychol Med. 2020

Kjærstad HL, Jørgensen CK, Broch-Due I, Kessing LV, Miskowiak K. Eye gaze and facial displays of emotion during emotional film clips in remitted patients with bipolar disorder. Eur Psychiatry. 2020

Miskowiak KW, Lewandowski KE. Trajectory of cognitive functions in bipolar disorder: for better or worse? Acta Psychiatr Scand. 2020 Feb;141(2):95-97.

Miskowiak KW, Forman JL, Vinberg M, Siebner HR, Kessing LV, Macoveanu J. Impact of pretreatment interhemispheric hippocampal asymmetry on improvement in verbal learning following erythropoietin treatment in mood disorders: a randomized controlled trial. J Psychiatry Neurosci. 2020 May 1;45(3):198-205

Miskowiak KW, Seeberg I, Kjaerstad HL, Burdick KE, Martinez-Aran A, Del Mar Bonnin C, Bowie CR, Carvalho AF, Gallagher P, Hasler G, Lafer B, López-Jaramillo C, Sumiyoshi T, McIntyre RS, Schaffer A, Porter RJ, Purdon S, Torres IJ, Yatham LN, Young AH, Kessing LV, Van Rheenen TE, Vieta E. Affective cognition in bipolar disorder: A systematic review by the ISBD targeting cognition task force. Bipolar Disord. 2020;21(8):686-719.

Vestergaard M, Kongerslev MT, Thomsen MS, Mathiesen BB, Harmer CJ, Simonsen E, Miskowiak KW. Women With Borderline Personality Disorder Show Reduced Identification of Emotional Facial Expressions and a Heightened Negativity Bias. J Pers Disord. 2020 Oct;34(5):677-698.

2019

Kjærstad HL, Eikeseth FF, Vinberg M, Kessing LV, Miskowiak K. Neurocognitive heterogeneity in patients with bipolar disorder and their unaffected relatives: associations with emotional cognition. Psychol Med. 2019 Dec 26:1-12.

Hørlyck LD, Macoveanu J, Vinberg M, Kessing LV, Siebner HR, Miskowiak KW. The BDNF Val66Met Polymorphism Has No Effect on Encoding-Related Hippocampal Response But Influences Recall in Remitted Patients With Bipolar Disorder. Front Psychiatry. 2019

Bjertrup AJ, Friis NK, Miskowiak KW. The maternal brain: Neural responses to infants in mothers with and without mood disorder. Neurosci Biobehav Rev. 2019 Dec;107:196-207.

Petersen JZ, Nilsson M, Rungby J, Miskowiak KW. Characteristics influencing expected cognitive performance during hypoglycaemia in type 2 diabetes. Psychoneuroendocrinology. 2019 Dec;110:104431.

Ottesen, N. M., Meluken, I., Frikke-Schmidt, R., Plomgaard, P., Scheike, T., Fernandes, B. S., … & Vinberg, M. (2019). Are remitted affective disorders and familial risk of affective disorders associated with metabolic syndrome, inflammation and oxidative stress?–a monozygotic twin study. Psychological medicine, 1-10.

Miskowiak, K. W., Seeberg, I., Kjaerstad, H. L., Burdick, K. E., Martinez‐Aran, A., Bonnin, C. M., … & Lafer, B. Affective cognition in bipolar disorder: A systematic review by the ISBD targeting cognition task force. Bipolar Disorders.

Kjærstad, H. L., Mistarz, N., Coello, K., Stanislaus, S., Melbye, S. A., Harmer, C. J., Vinberg, M., Miskowiak, K. W. & Kessing, L. V. (2019). Aberrant cognition in newly diagnosed patients with bipolar disorder and their unaffected relatives. Psychological medicine, 1-12.

Ott, C., Miné, H., Petersen, J. Z., & Miskowiak, K. (2019). Relation between functional and cognitive impairments in remitted patients with bipolar disorder and suggestions for trials targeting cognition: An exploratory study. Journal of affective disorders, 257, 382-389.

Meluken, I., Ottesen, N., Harmer, C., Macoveanu, J., Siebner, H., Kessing, L., … & Miskowiak, K. (2019). Neural response to emotional faces in monozygotic twins: association with familial risk of affective disorders. Journal of psychiatry & neuroscience: JPN, 44(3), 1-10.

Ott, C. V., Johnson, C. B., Macoveanu, J., & Miskowiak, K. (2019). Structural changes in the hippocampus as a biomarker for cognitive improvements in neuropsychiatric disorders: A systematic review. European Neuropsychopharmacology.

Petersen, J. Z., Porter, R. J., & Miskowiak, K. W. (2019). Clinical characteristics associated with the discrepancy between subjective and objective cognitive impairment in depression. Journal of affective disorders, 246, 763-774.

Meluken, I., Ottesen, N. M., Phan, K. L., Goldin, P. R., Di Simplicio, M., Macoveanu, J., … & Miskowiak, K. W. (2019). Neural response during emotion regulation in monozygotic twins at high familial risk of affective disorders. NeuroImage: Clinical, 21, 101598.

2018

Ottesen, N. M., Meluken, I., Scheike, T., Kessing, L. V., Miskowiak, K. W., & Vinberg, M. (2018). Clinical characteristics, life adversities and personality traits in monozygotic twins with, at risk of and without affective disorders. Frontiers in psychiatry, 9.

Petersen, J. Z., Schmidt, L. S., Vinberg, M., Jørgensen, M. B., Hageman, I., Ehrenreich, H., Knudsen, G.M., Kessing, L.V., & Miskowiak, K. W. (2018). Effects of recombinant human erythropoietin on cognition and neural activity in remitted patients with mood disorders and first-degree relatives of patients with psychiatric disorders: a study protocol for a randomized controlled trial. Trials, 19(1), 611.

Kessing, L. V., & Miskowiak, K. (2018). Does Cognitive Dysfunction in Bipolar Disorder Qualify as a Diagnostic Intermediate Phenotype?—A Perspective Paper. Frontiers in Psychiatry, 9.

Ottesen, N. M., Meluken, I., Scheike, T., Kessing, L. V., Miskowiak, K. W., & Vinberg, M. (2018). Clinical Characteristics, Life Adversities and Personality Traits in Monozygotic Twins With, at Risk of and Without Affective Disorders. Frontiers in psychiatry, 9.

Ott, C. V., Vinberg, M., Bowie, C. R., Christensen, E. M., Knudsen, G. M., Kessing, L. V., & Miskowiak, K. W. (2018). Effect of action-based cognitive remediation on cognition and neural activity in bipolar disorder: study protocol for a randomized controlled trial. Trials, 19(1), 487.

Miskowiak, K. W., & Petersen, C. S. (2018). Neuronal underpinnings of cognitive impairment and-improvement in mood disorders. CNS spectrums, 1-24.

Seeberg, I., Kjærstad, H. L., & Miskowiak, K. (2018). Neural and behavioral predictors of treatment efficacy on mood symptoms and cognition in mood disorders: A systematic review. Frontiers in psychiatry, 9, 337.

Macoveanu, J., Demant, K. M., Vinberg, M., Siebner, H. R., Kessing, L. V., & Miskowiak, K. W. (2018). Towards a biomarker model for cognitive improvement: No change in memory-related prefrontal engagement following a negative cognitive remediation trial in bipolar disorder. Journal of Psychopharmacology, 32(10), 1075-1085.

Meluken, I., Ottesen, N. M., Harmer, C. J., Scheike, T., Kessing, L. V., Vinberg, M., & Miskowiak, K. W. (2018). Is aberrant affective cognition an endophenotype for affective disorders?–A monozygotic twin study. Psychological medicine, 1-10.

Miskowiak, K. W., Macoveanu, J., Jørgensen, M. B., Ott, C. V., Støttrup, M. M., Jensen, H. M., … & Kessing, L. V. (2018). Effect of electroconvulsive therapy on neural response to affective pictures: A randomized, sham-controlled fMRI study. European Neuropsychopharmacology.

Miskowiak, K. W., Petersen, N. A., Harmer, C. J., Ehrenreich, E., Kessing, L. V., Vinberg, M., … & Siebner, H. R. (2018). Neural correlates of improved recognition of happy faces after erythropoietin treatment in bipolar disorder. Acta Psychiatrica Scandinavica, 138(4), 336-347.

Broch-Due, I., Kjærstad, H. L., Kessing, L. V., & Miskowiak, K. (2018). Subtle behavioural responses during negative emotion reactivity and down-regulation in bipolar disorder: A facial expression and eye-tracking study. Psychiatry research, 266, 152-159.

Petersen, J. Z., & Miskowiak, K. W. (2018). Cognitive side effects of electroconvulsive therapy. Ugeskrift for laeger, 180(18).

Miskowiak, K. W., Macoveanu, J., Jørgensen, M. B., Støttrup, M. M., Ott, C. V., Jensen, H. M., … & Siebner, H. R. (2017). Neural response after a single ECT session during retrieval of emotional self-referent words in depression: a randomized, sham-controlled fMRI study. International Journal of Neuropsychopharmacology, 21(3), 226-235.

Schmidt, L. S., Petersen, J. Z., Vinberg, M., Hageman, I., Olsen, N. V., Kessing, L. V., … & Miskowiak, K. W. (2018). Erythropoietin as an add-on treatment for cognitive side effects of electroconvulsive therapy: a study protocol for a randomized controlled trial. Trials, 19(1), 234.

Kærsgaard, S., Meluken, I., Kessing, L. V., Vinberg, M., & Miskowiak, K. W. (2018). Increased sensitivity to positive social stimuli in monozygotic twins at risk of bipolar vs. unipolar disorder. Journal of affective disorders, 232, 212-218.

Miskowiak, K. W., Burdick, K. E., Martinez‐Aran, A., Bonnin, C. M., Bowie, C. R., Carvalho, A. F., … & McIntyre, R. S. (2018). Assessing and addressing cognitive impairment in bipolar disorder: the International Society for Bipolar Disorders Targeting Cognition Task Force recommendations for clinicians. Bipolar disorders, 20(3), 184-194